Proton Pump Inhibitor Usage in Urban vs. Rural Intensive Care Units: A Narrative Review of Implications for Standardization of Care

Publications Category : Emergency Medicine, Gastroenterology, General Surgery / Surgery

Author(s): Gaurav Prabhu MD, Michael Murray, Sarah J. Scherbring, Sainamitha R. Palnati, Saajan Bhakta PhD

Project Description : Intensive care unit (ICU) patients frequently require and benefit from stress ulcer prophylaxis (SUP) using proton pump inhibitors (PPIs). Despite recognized benefits, PPIs are overutilized in patients who do not have high-risk factors predisposing them to clinically significant gastrointestinal bleeding (CSGIB). This narrative review aimed to assess current data on PPI usage in both urban and rural critical care environments, and to appraise existing practices, ultimately identifying gaps in current literature and informing future guidelines.